Same word as nochance:

at end of one's rope, back to the wall, can't win, dead duck, despairing, despondent, desponding, downcast, forlorn, futile, gone, goner, hard up, in the soup, in the toilet, inconsolable, irrecoverable, irremediable, irretrievable, no-chance, no-way, no-win, running out of time, sad, sunk, up against it, up the creek, useless, vain, wretched